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Basic Info

  • Grade: pharmaceutical grade

    Factory Location: china

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Eastern Europe,Australasia,Asia,Middle East,Africa

  • Packaging Information: 1kg/bag

  • Sample Provided: no

    Payment Terms: Bank transfer

    2,4,5-Trifluorobenzyl bromide is an important intermediate in the synthesis of sitagliptin. Sitagliptin is the first dipeptidyl peptidase-IV (DPP-IV) inhibitor developed by Merck and approved by the US FDA in October 2006 for the treatment of non-insulin-dependent (type II) diabetes. 2,4,5-trifluorobenzyl bromide is prepared by bromomethylation of 1,2,4-trifluorobenzene as raw material, which has more waste and needs to use highly toxic cyanide, and the process has certain safety risks.
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    Chongqing Xingcan Pharmaceutical Technology Co., Ltd
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