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Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: Shanghai

    Main Sales Markets: Western Europe,Eastern Europe,Asia

  • Sample Provided: no

    Shanghai Linzyme Biosciences Ltd.Deoxyribonuclease I - Shanghai Linzyme Biosciences Ltd.

    Source: Bovine Pancrease
    EC: 3.1.21.1

    DESCRIPTION
      Bovine pancreatic deoxyribonuclease (DNase) is an endonuclease which splits phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide yielding polynucleotides with free hydroxyl group at the 3' position and phosphate group at the 5' position. The optimum pH is 7.8. DNase I is activated by bivalent metals, and inhibited by chelating agents such EDTA and sodium dodecyl sulfate. DNase I can be stabilized against proteolytic digestion by 5 mM Ca2+.
      Linzyme Deoxyribonuclease has been chromatographically purified to remove trace contaminating proteases. DNase may be used in clinic to thin and liquefy mucus in the lungs.

    SPECIFICATION (I)

    Item

    Specifications

    Methods

    Appearance

    White or pale yellow lyophilized powder

     

    Activity

    ≥ 3,000 Christensen units/mg powder

    K.P.

    Loss on drying

    ≤ 0.3%

    K.P.

    Residue on ignition

    ≤ 1.0%

    K.P.

    Conclusion: Product complies with KP.

    SPECIFICATION (II)

    Activity

    ≥ 500 Kunitz units/mg powder

    Sigma-aldrich

    SPECIFICATION (III)

    Activity

    ≥ 2,000 Kunitz units/mg powder

    Sigma-aldrich

     STORAGE
       Store in an airtight container, at a temperature of 2°C to 8°C.

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    Ningbo Linzyme Biosciences Co., Ltd.
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