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Basic Info

  • Grade: Pharmaceutical Grade

    Factory Location: shandong

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Asia,Middle East,Africa

  • Monthly Production Capacity: 100kgs

    Contract Manufacturing: CRO,CMO

    Packaging Information: as request

  • Sample Provided: yes

    Payment Terms: T/T

    Description

    Geneticin (G418) Sulfate is an aminoglycoside antibiotic that has originally been derived from Micromonospora rhodoranga NRRL 5326. This compound has been shown to cause a bypass of nonsense mutations during translation. Experiments have shown that geneticin sulfate inhibits the incorporation of amino acids into protein and can destroy fibroblasts. Mechanistic studies suggest that this agent affects the 80S ribosome and inhibits the elongation cycle. Further studies report that geneticin sulfate is highly active against amoebae, protozoa, tapeworm, and pinworm exposed murine cells.

    Usage

    • Potency: ≥700 μg/mg

    Technical Information

    Appearance: Powder
    Physical State: Solid
    Solubility: Soluble in water (50 mg/ml) and aqueous buffers.
    Storage: Store at 4° C
    Boiling Point: 1012.1 °C at 760 mmHg (Predicted)
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    Beijing Global Biologicals Co.Ltd
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