Pharmaceutical Grade API Perampanel CAS 380917-97-5

Category:Active Pharmaceutical Ingredients > Other Active Pharmaceutical Ingredients
Product Name:Pharmaceutical Grade API Perampanel CAS 380917-97-5
CAS No.:380917-97-5
Standard:ChP, USP, BP, EP, JP, IP, Ph. Int
Price(USD):$1000/kg-$2000/kg
Company:Shandong Loncom Pharmaceutical Co.Ltd.

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Basic Info

Grade: Pharmaceutical Grade

Factory Location: China

Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa
Monthly Production Capacity: 100kg

Contract Manufacturing: CRO,CMO

Packaging Information: 5kg/drum
Delivery Lead Time: 15days

Sample Provided: yes

Payment Terms: T/T

Perampanel is an orally active, non-competitive, and selective alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptor antagonist, with anti-epileptic activity. Although the mechanism of action through which perampanel exerts its antiepileptic effect has not been fully elucidated, this agent antagonizes the AMPA subtype of the excitatory glutamate receptor found on postsynaptic neurons in the central nervous system (CNS). This antagonistic action prevents AMPA receptor activation by glutamate and results in the inhibition of neuronal excitation, repetitive neuronal firing, and the stabilization of hyper-excited neural membranes. Glutamate, the primary excitatory neurotransmitter in the CNS, plays an important role in various neurological disorders caused by neuronal hyperexcitation.

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