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  • Grade: pharmaceutical grade

    Factory Location: china

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Eastern Europe,Australasia,Asia,Middle East,Africa

  • Packaging Information: 1kg/bag

  • Sample Provided: no

    Payment Terms: Bank transfer

    Tetrahydroxydiboron is mainly used in Suzuki conjugation to synthesize pharmaceutical intermediates. The earliest synthesis of tetrahydroxydiboron can be traced back to 1955, Wartik uses a zinc electrode inserted into liquid boron trichloride to generate boron tetrachloride, and then boron tetrachloride reacts with water to first generate tetrahydroxydiboron, and then heated to 220 °C to dehydrate to generate (BO)X; Chemicalbook In 1961, McCloskey used a drop of quantitative hydrochloric acid to add tetra(dimethylamino)biboron and water mixture at 0 °C to generate tetrahydroxydiboron with a yield of 56%. For nearly fifty years, there was almost no published method in the literature, until 2012, when Molander again mentioned the use of the latter method to synthesize tetrahydroxydiboron.
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