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Basic Info

  • Grade: Cosmetic Grade

    Factory Location: Xiamen Fujian

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

  • Monthly Production Capacity: 10ton/year

    Packaging Information: 25kg/drum; 5kg/bag, 1kg/bag

  • Delivery Lead Time: 7 days after payment

    Sample Provided: yes

    Payment Terms: L/L

    Product Information

     

    Product name

    Vitamin A acid / Tretinoin / Retinoic Acid

    CAS No.

    302-79-4

    Molecular Formula

    C20H28O2

    Molecular Weight

    4300.44

    Quality Standard

    99% up, Cosmetic Grade

    Appearance

    Light yellow powder

     

    COA of Vitamin A acid / Tretinoin / Retinoic Acid

     

    Items

    Specification

    Results

    Appearance

    Yellow Powder

    Complies

    Odor

    Characteristic

    Complies

    Sieve analysis

    100% pass 80mesh

    Complies

    Heavy Metal

    < 10ppm

    Complies

    Ash

    ≤1.0%

    0.22%

    Pb

    ≤2.0ppm

    Not Detected

    As

    ≤0.1pm

    Not Detected

    Cd

    ≤0.3ppm

    Not Detected

    Residual Solvents

    ≤100ppm

    Complies

    Residual Pesticide

     Negative

    Complies

    Total Plate Count

    ≤1,000cfu/g

    Complies

    Mold and Yeast

    ≤100cfu/g

    Complies

    E.Coli

    Negative

    Negative

    Salmonella

    Negative

    Negative

    Related substance      (HPLC)

    98% min

    99.8%

    Assay

    98%

    98.22%

    Conclusion

     Complies with In-house standard

                                                 

     

    Usage

     

    Retinoic acid (is also called Vitamin A acid / Tretinoin /) is a metabolite of vitamin A and plays an important role in cell growth, differentiation and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptor α/β/γ The IC50 is 14 nm. Retinoic acid and PPAR β/δ  The combined Kd value is 17 nm. Retinoic acid can inhibit transcription factor Nrf2 by activating retinoic acid receptor.

     

    Function of Retinoic Acid
    1. Retinoic acid is the acid form of vitamin a and so also known as all-trans retinoic acid or atra.

    2. Retinoic acid is a drug commonly used to treat acne vulgaris and keratosis pilaris.

    3. Retinoic acid is available as a cream or gel.retinoic acid is also used to treat acute promyelocytic leukemia.

    4. Retinoic acid can stimulate skin growth and keep epidermic normal.

    5. Retinoic acid can slow down skin aging process for solarization, remove tiny wrinkles, and retinoic acid canreduce skin roughness, so skin will become ruddy.

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