BioNTech SE announced the launch of its Malaria project, which aims to develop a well-tolerated and highly effective Malaria vaccine and implement sustainable vaccine supply solutions on the African continent.

BioNTech’s Malaria project has two key objectives:

• First, is to develop a safe and highly effective mRNA vaccine with durable protective immunity to prevent Malaria and disease-associated mortality. 

• Second, is to develop sustainable vaccine production and supply solutions on the African continent. 

“The response to the pandemic has shown that science and innovation can transform people's lives when all key stakeholders work together towards a common goal. We are committed to bringing our innovations to those who need them most,” said Prof. Dr. Ugur Sahin, CEO and co-founder of BioNTech. “We are more than grateful to be part of the joint efforts of the Eradicate Malaria project. Together with our partners, we will do whatever it takes to develop a safe and effective mRNA-based Malaria vaccine that will prevent the disease, reduce mortality and ensure a sustainable solution for the African continent and other regions affected by this disease. Our efforts will include cutting-edge research and innovation, significant investments in vaccine development, the establishment of manufacturing facilities, and the transfer of manufacturing expertise to production sites on the African continent and wherever else it is needed.”

BioNTech has undertaken comprehensive antigen discovery processes to identify antigens for various vaccine candidates. Since 2019, the Company has collaborated with the Bill and Melinda Gates foundation to develop Human Immunodeficiency Virus (HIV) and Tuberculosis programs and provide affordable access to vaccines to low- and middle-income countries. For Tuberculosis, BioNTech plans to begin clinical trials for testing a vaccine candidate in 2022, just about two years after the program was initiated. The antigen discovery processes for Malaria and Tuberculosis are being conducted by specialized teams at BioNTech’s headquarters in Mainz. Currently, BioNTech and its partners are developing vaccines against nine different infectious diseases, and the Company continues to develop 15 oncology programs at clinical stage based on four different drug classes, including mRNA.

The World Health Organization (WHO), European Commission and other organizations have been involved in the early planning phase of BioNTech’s Malaria project and have offered their support to identify and set up the necessary infrastructure. Collaboration with the African Union and the Africa CDC under the partnership for African Vaccine Manufacturing program will ensure that the enabling factors such as regulatory alignment and policy transfer, as well as country coordination are in place to get the vaccines from factories to the citizens of the African Union.