Ⅰ. The status quo of the dropping pill machine

Today, dripping pill preparations have officially become a highly regarded preparation in the pharmaceutical industry. In a sense, the dripping pill preparation is a "solid-liquid preparation" prepared by using solid loosening technology. The dropping pill machine has the advantages of fast dissolution, high bioavailability, good function, simple preparation, and easy control of quality. Because of the characteristics of the dripping pill machine itself, the development of new technologies in recent years, the emergence of new auxiliary materials, and the gradual improvement of pharmaceutical equipment, the dripping pill preparation technology of the dripping pill machine has been deeply studied and widely used. The dropping pill machine has broad prospects in the research and development of new dosage forms of Chinese medicine.

Ⅱ. Commonly used laboratory dropping pill machines are divided into three categories

There are very significant differences between using the dripping machine to make dripping pill preparations and traditional preparations. The dripping pill machine has the following characteristics:

1. Fast absorption: The dripping pill prepared with a water-soluble matrix has a dissolution time limit of 5 to 15 minutes, not more than 30 minutes, so it takes effect quickly;

2. In addition to oral administration, the dripping pills can also be taken sublingually. They are directly absorbed into the blood through the oral mucosa and have a faster onset of action.

The dripping pill machine for preparing dripping pills is mainly composed of a dropper, a heat preservation device, a device for controlling the condensation temperature, a condenser container, etc.

The commonly used drop pill machines can be divided into three categories:

1. For the downward-dropping small-dropping pill machine, the liquid medicine is naturally dripped from the nozzle of the dripper due to the energy and gravity. The weight of the pill is mainly controlled by the diameter of the dripper. When the mouth of the tube is too thick, the liquid medicine is not full, which increases the difference in pill weight. Therefore, this dropping pill machine can only produce small droplets with a pill weight below 70mg.

2. The big drop pill machine can be used with a quantitative pump, and the weight of the pill can be controlled by the stroke of the plunger.

3. The dripping pill machine with upward dripping is used for the type whose liquid medicine proportion is less than that of condensate.